There is evidence to suggest that clinically proven Agnus Castus is a dopamine agonist which intervenes in the control of the menstrual cycle. Certain preparations are similar to the endogenous neurotransmitter, dopamine, and thus it can reduce the secretion of the hormone prolactin. High levels of prolactin are often the cause of cycle irregularities and cycle difficulties.
In fact, certain medications containing Agnus Castus extract claim that they can deal with the complaints and causes of PMS, and not just suppressing the symptoms e.g. with analgesics. They restore the hormonal balance, thus the rhythm of the cycle can be harmonised. Too short or too long cycles can be corrected to within the normal 28 day cycle.
There are several Agnus Castus preparations available but only certain Agnus Castus products that are manufactured uniquely have been shown in several clinical trials to be effective in PMS. Furthermore, these same products from the same manufacturer have been shown to have a dopamine agonistic action which is important in controlling the menstrual cycle. This elevated dopamine then leads to a reduction of prolactin levels which relieve breast pain and harmonises the menstrual cycle. High levels of prolactin are often the cause of cycle irregularities and cycle difficulties.
In several clinical trials these Agnus Castus products have been shown to be effective in the management of physical and emotional symptoms of PMS.
In addition, symptoms such as pain, stress, swelling and a feeling of heaviness in the breasts are relieved, irritability subsides, water retention reduces, digestive problems and headaches occur less often.